Science-Driven
Skin Health
Protocols
Medical-grade skincare programs engineered to cleanse, correct, and protect — for every skin type, tone, and concern. Backed by 35+ years of clinical research.
*89% Improvement in skin hydration by week 4 *98% Improvement in fine lines by week 12 *35+Years of clinical research
Getting Skin Ready®
The non-negotiable first step of any ZO® regimen. GSR® brings skin back to its most healthy, balanced state — preparing it to absorb every active ingredient that follows. A simple 3-step system of cleansing, exfoliating, and toning that forms the essential base for all ZO® protocols.
1.Cleanse — AM & PMGentle Cleanser or Exfoliating Cleanser — removes impurities, makeup, and excess oils for a clean, absorbent base.
2. Exfoliate — 2–3×/weekExfoliating Polish — ultra-fine magnesium oxide crystals slough dead skin cells to reveal smoother, glowing skin.
3.Tone — AM & PMComplexion Renewal Pads — glycolic + salicylic acids to brighten, smooth, and decongest pores.
Daily Skincare Program
The foundational ZO® regimen for anyone beginning their skin health journey. This four-step travel-friendly system cleanses, exfoliates, and preps skin while delivering daily antioxidant protection with Daily Power Defense — benefiting every skin type.
1 Exfoliating Cleanser — AM & PMClears pores and provides both physical and chemical exfoliation in a single step.
2 Exfoliating Polish — 2–3×/weekReveals smoother, softer, glowing skin by removing dead skin cells and surface debris.
3 Complexion Renewal Pads — AM & PMBrightens, clarifies pores, and soothes irritation in one wipe.
4 Daily Power Defense — AM & PMNext-generation antioxidant serum that firms, protects against environmental damage, and defends against premature aging.
Anti-Aging Program
A moderate program for the reduction of early or significant signs of environmental and chronological aging. Features Growth Factor Serum — clinically proven to enhance visible skin thickness, elasticity, smoothness, and suppleness using plant-derived growth factors.
AM Exfoliating Cleanser + Exfoliating PolishCleanse and exfoliate away surface debris
AM Complexion Renewal Pads + Daily Power Defense Tone and antioxidant protection
PM Growth Factor SerumOne pump over face and neck every evening
Complexion Clearing (Acne) Program
A comprehensive program designed to minimize excess surface oil, unclog and cleanse pores, and eliminate future breakouts. The sulfur-based Complexion Clearing Masque targets blemishes at the source while the full-size Exfoliating Cleanser provides daily deep-pore cleansing.
AM/PM Exfoliating CleanserDeep-cleanse and decongest pores daily
2–3×/wk Exfoliating PolishRemove dead skin cells and surface buildup
AM/PM Complexion Renewal PadsTone and decongest with glycolic + salicylic acids
PM Complexion Clearing MasqueSulfur-based masque targets active breakouts and unclogs pores
Skin Brightening Program
A hydroquinone-free and retinol-free system designed for the improvement of visible discoloration — ideal for freckles, liver spots, and uneven skin tone including those with sensitive skin. Clinically proven Brightalive® fades the appearance of dark spots for a luminous complexion.
AM/PM Gentle CleanserCleanse without stripping or irritating
AM/PM Exfoliating Polish + Complexion Renewal PadsExfoliate and tone skin surface
AM/PM Daily Power Defense + Brightalive®Protect and brighten for even skin tone
Redness Relief + Barrier Defense Program
A complete 6-step system formulated to improve skin barrier function and combat multiple factors that lead to skin sensitization and redness. At its core is clinically proven Rozatrol® — a patented multi-modal serum shown to relieve multiple symptoms of redness-prone and rosacea-prone skin.
AM/PM Gentle CleanserMild formula that cleanses without stripping sensitive skin
AM/PM Exfoliating Polish + Calming TonerGently exfoliate and restore pH balance
AM/PM Daily Power Defense + Rozatrol®Protect barrier and soothe visible redness
AM/PM Soothing Hydro MistDelivers immediate hydration and calms visible redness